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Thrombocythemia may lead to . Microvascular occlusions. Large vessel thrombosis . Bleeding. Microvascular occlusions involve small vessels of the distal extremities (causing。

ET usually develops very slowly. It can affect people of any age. But it usually affects middle aged and older people. The average age at diagnosis is about 65 years although it can affect children and young adults.

Overview: Essential thrombocythemia is a Janus kinase 2 (JAK2) mutation-prevalent myeloproliferative neoplasm characterized by clonal thrombocytosis; clinical course is often。

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